Discover the scenic wonders of East Tennessee with vacation rentals by owner that combine comfort, charm, and a personal touch. From the majestic Great Smoky Mountains to the vibrant cities of Knoxville and Johnson City, this region offers something for every traveler. Choose from cozy mountain cabins, lakefront homes, and countryside retreats—many featuring full kitchens, Wi-Fi, and pet-friendly options. Enjoy hiking, fishing, and exploring historic towns, scenic byways, and national parks. Whether you're seeking outdoor adventure or a peaceful escape, the East Region of Tennessee delivers. Book directly with owners for great value, local insight, and a welcoming home-away-from-home experience.